VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis

Release of promoter-proximally paused RNA polymerase II (RNAPII) is a recently recognized transcriptional regulatory checkpoint. The biological roles of RNAPII pause release and the mechanisms by which extracellular signals control it are incompletely understood. Here we show that VEGF stimulates RN...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chen, Jiahuan, Fu, Yi, Day, Daniel S., Sun, Ye, Wang, Shiyan, Liang, Xiaodong, Gu, Fei, Zhang, Fang, Stevens, Sean M., Zhou, Pingzhu, Li, Kai, Zhang, Yan, Lin, Ruei-zeng, Smith, Lois E. H., Zhang, Jin, Sun, Kun, Melero-Martin, Juan M., Han, Zeguang, Park, Peter J., Zhang, Bing, Pu, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575285/
https://ncbi.nlm.nih.gov/pubmed/28851877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00405-x
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