Intravenous rAAV2/9 injection for murine cochlear gene delivery

Gene therapy for genetic deafness is a promising approach by which to prevent hearing loss or to restore hearing after loss has occurred. Although a variety of direct approaches to introduce viral particles into the inner ear have been described, presumed physiological barriers have heretofore precl...

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Udgivet i:Sci Rep
Main Authors: Shibata, Seiji B., Yoshimura, Hidekane, Ranum, Paul T., Goodwin, Alexander T., Smith, Richard J. H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575199/
https://ncbi.nlm.nih.gov/pubmed/28852025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09805-x
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