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The histidine-rich peptide LAH4-L1 strongly promotes PAMAM-mediated transfection at low nitrogen to phosphorus ratios in the presence of serum

Non-viral vectors are widely used and investigated for the delivery of genetic material into cells. However, gene delivery barriers like lysosomal degradation, serum inhibition and transient gene expression so far still limit their clinical applications. Aiming to overcome these limitations, a pH-se...

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Pubblicato in:Sci Rep
Autori principali: Liu, Nan, Bechinger, Burkhard, Süss, Regine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575053/
https://ncbi.nlm.nih.gov/pubmed/28852016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10049-y
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