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NMR Structures of the Histidine-Rich Peptide LAH4 in Micellar Environments: Membrane Insertion, pH-Dependent Mode of Antimicrobial Action, and DNA Transfection

The LAH4 family of histidine-rich peptides exhibits potent antimicrobial and DNA transfection activities, both of which require interactions with cellular membranes. The bilayer association of the peptides has been shown to be strongly pH-dependent, with in-planar alignments under acidic conditions...

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Bibliografske podrobnosti
Main Authors: Georgescu, Julia, Munhoz, Victor H.O., Bechinger, Burkhard
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955508/
https://ncbi.nlm.nih.gov/pubmed/20959091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.038
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