Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction

Conventional protein kinase C βI (cPKCβI) is a conventional protein kinase C (PKC) isoform directly involved in the regulation of neurotransmitter release in the neuromuscular junction (NMJ). It is located exclusively at the nerve terminal and both synaptic activity and muscle contraction modulate i...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Hurtado, Erica, Cilleros, Víctor, Just, Laia, Simó, Anna, Nadal, Laura, Tomàs, Marta, Garcia, Neus, Lanuza, Maria A., Tomàs, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574929/
https://ncbi.nlm.nih.gov/pubmed/28890686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00270
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