Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction

Conventional protein kinase C βI (cPKCβI) is a conventional protein kinase C (PKC) isoform directly involved in the regulation of neurotransmitter release in the neuromuscular junction (NMJ). It is located exclusively at the nerve terminal and both synaptic activity and muscle contraction modulate i...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Hurtado, Erica, Cilleros, Víctor, Just, Laia, Simó, Anna, Nadal, Laura, Tomàs, Marta, Garcia, Neus, Lanuza, Maria A., Tomàs, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574929/
https://ncbi.nlm.nih.gov/pubmed/28890686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00270
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