Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction

Conventional protein kinase C βI (cPKCβI) is a conventional protein kinase C (PKC) isoform directly involved in the regulation of neurotransmitter release in the neuromuscular junction (NMJ). It is located exclusively at the nerve terminal and both synaptic activity and muscle contraction modulate i...

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Udgivet i:Front Mol Neurosci
Main Authors: Hurtado, Erica, Cilleros, Víctor, Just, Laia, Simó, Anna, Nadal, Laura, Tomàs, Marta, Garcia, Neus, Lanuza, Maria A., Tomàs, Josep
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574929/
https://ncbi.nlm.nih.gov/pubmed/28890686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00270
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