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Activation of invariant natural killer T cells stimulated with microbial α-mannosyl glycolipids
Some synthetic and bacterial glycolipids presented by CD1d specifically activate invariant NKT (iNKT) cells bearing an invariant Vα14-Jα18 (mouse) or Vα24-Jα18 (human) TCR. The antigenic glycolipids identified to date consist of two hydrophobic chains and an α-glycoside in which the 2′-OH group is i...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5574887/ https://ncbi.nlm.nih.gov/pubmed/28852174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10309-x |
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