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Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions

It has been previously observed that the intrinsically weak variant GC donor sites, in order to be recognized by the U2-type spliceosome, possess strong consensus sequences maximized for base pair formation with U1 and U5/U6 snRNAs. However, variability in signal strength is a fundamental mechanism...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Thanaraj, T. A., Clark, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55748/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11410667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.12.2581
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