Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions
It has been previously observed that the intrinsically weak variant GC donor sites, in order to be recognized by the U2-type spliceosome, possess strong consensus sequences maximized for base pair formation with U1 and U5/U6 snRNAs. However, variability in signal strength is a fundamental mechanism...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11410667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.12.2581 |
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