Accurate quantification of chromosomal lesions via short tandem repeat analysis using minimal amounts of DNA

BACKGROUND: Cytogenetic aberrations such as deletion of chromosome 5q (del(5q)) represent key elements in routine clinical diagnostics of haematological malignancies. Currently established methods such as metaphase cytogenetics, FISH or array-based approaches have limitations due to their dependency...

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Udgivet i:J Med Genet
Main Authors: Jann, Johann-Christoph, Nowak, Daniel, Nolte, Florian, Fey, Stephanie, Nowak, Verena, Obländer, Julia, Pressler, Jovita, Palme, Iris, Xanthopoulos, Christina, Fabarius, Alice, Platzbecker, Uwe, Giagounidis, Aristoteles, Götze, Katharina, Letsch, Anne, Haase, Detlef, Schlenk, Richard, Bug, Gesine, Lübbert, Michael, Ganser, Arnold, Germing, Ulrich, Haferlach, Claudia, Hofmann, Wolf-Karsten, Mossner, Maximilian
Format: Artigo
Sprog:Inglês
Udgivet: Journal of Medical Genetics 2017
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Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574397/
https://ncbi.nlm.nih.gov/pubmed/28600436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2017-104528
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