Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid

5-azacytidine (AZA) has become standard treatment for patients with higher-risk myelodysplastic syndrome (MDS). Response rate is about 50% and response duration is limited. Histone deactylase (HDAC) inhibitors are attractive partners for epigenetic combination therapy. We treated 24 patients with AZ...

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Detalhes bibliográficos
Main Authors: Kuendgen, Andrea, Bug, Gesine, Ottmann, Oliver G., Haase, Detlef, Schanz, Julie, Hildebrandt, Barbara, Nachtkamp, Kathrin, Neukirchen, Judith, Dienst, Ariane, Haas, Rainer, Germing, Ulrich, Gattermann, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365387/
https://ncbi.nlm.nih.gov/pubmed/22704349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13148-011-0031-9
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