De Novo MS/MS Sequencing of Native Human Antibodies

One direct route for the discovery of therapeutic human monoclonal antibodies (mAbs) involves the isolation of peripheral B cells from survivors/sero-positive individuals after exposure to an infectious reagent or disease etiology followed by single-cell sequencing or hybridoma generation. Periphera...

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Foilsithe in:J Proteome Res
Main Authors: Guthals, Adrian, Gan, Yutian, Murray, Laura, Chen, Yongmei, Stinson, Jeremy, Nakamura, Gerald, Lill, Jennie R, Sandoval, Wendy, Bandeira, Nuno
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574256/
https://ncbi.nlm.nih.gov/pubmed/27779884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00608
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