Φορτώνει......
mTOR Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice
OBJECTIVE: Elastin deficiency due to heterozygous loss of an ELN allele in Williams syndrome causes obstructive aortopathy characterized by medial thickening and fibrosis and consequent aortic stiffening. Previous work in Eln-null mice with a severe arterial phenotype showed that inhibition of mecha...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Arterioscler Thromb Vasc Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5574180/ https://ncbi.nlm.nih.gov/pubmed/28751568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309653 |
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