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A novel mutation in the COL2A1 gene in a patient with Stickler syndrome type 1: a case report and review of the literature

BACKGROUND: Stickler syndrome is a group of collagenopathies characterized by ophthalmic, skeletal, and orofacial abnormalities, with the degree of symptoms varying among patients. Mutations in the COL2A1, COL11A1, and COL11A2 procollagen genes cause Stickler syndrome. Marshall syndrome, caused by a...

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Detalhes bibliográficos
Publicado no:J Med Case Rep
Main Authors: Higuchi, Yousuke, Hasegawa, Kosei, Yamashita, Miho, Tanaka, Hiroyuki, Tsukahara, Hirokazu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574094/
https://ncbi.nlm.nih.gov/pubmed/28841907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13256-017-1396-y
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