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Evidence of a Prion-Like Transmission of p53 Amyloid in Saccharomyces cerevisiae
Loss of p53 function is largely responsible for the occurrence of cancer in humans. Aggregation of mutant p53 has been found in multiple cancer cell types, suggesting a role of aggregation in loss of p53 function and cancer development. The p53 protein has recently been hypothesized to possess a pri...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5574041/ https://ncbi.nlm.nih.gov/pubmed/28630281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00118-17 |
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