Unstable transformation of mouse 3T3 cells by transfection with DNA from normal human lymphocytes.

DNA fragments (0.5-4.5 kb) of normal human lymphocytes induced pre-neoplastic mouse NIH/3T3 cells after transfection to grow in soft agar medium at low efficiency (0.0007 colonies/micrograms DNA/10(6) cells). In secondary transfections high mol. wt. DNA (greater than 20 kb) of cells transformed by D...

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Bibliographic Details
Main Authors: Schäfer, R, Griegel, S, Dubbert, M A, Willecke, K
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC557403/
https://ncbi.nlm.nih.gov/pubmed/6714229
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