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Understanding the mTOR signaling pathway via mathematical modeling

The mechanistic target of rapamycin (mTOR) is a central regulatory pathway that integrates a variety of environmental cues to control cellular growth and homeostasis by intricate molecular feedbacks. In spite of extensive knowledge about its components, the molecular understanding of how these funct...

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Detalhes bibliográficos
Publicado no:Wiley Interdiscip Rev Syst Biol Med
Main Authors: Sulaimanov, Nurgazy, Klose, Martin, Busch, Hauke, Boerries, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573916/
https://ncbi.nlm.nih.gov/pubmed/28186392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1379
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