Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics

There is growing interest in using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) derivatives for tissue regeneration. However, an increased understanding of human immune responses to stem cell-derived allografts is necessary for maintaining long-term graft persistence. To model...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Kooreman, Nigel G., de Almeida, Patricia E., Stack, Jonathan P., Nelakanti, Raman V., Diecke, Sebastian, Shao, Ning-Yi, Swijnenburg, Rutger-Jan, Sanchez-Freire, Veronica, Matsa, Elena, Liu, Chun, Connolly, Andrew J., Hamming, Jaap F., Quax, Paul H.A., Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Wu, Joseph C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573767/
https://ncbi.nlm.nih.gov/pubmed/28834758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.003
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