Early and late change on the preclinical Alzheimer’s cognitive composite in clinically normal older individuals with elevated β-amyloid

INTRODUCTION: Sensitive detection of cognitive decline over the course of preclinical Alzheimer’s disease is critical as the field moves toward secondary prevention trials. METHODS: We examined Aβ-related change in several variations of the preclinical Alzheimer cognitive composite (PACC) and each i...

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Veröffentlicht in:Alzheimers Dement
Hauptverfasser: Mormino, Elizabeth C., Papp, Kathryn V., Rentz, Dorene M., Donohue, Michael C., Amariglio, Rebecca, Quiroz, Yakeel T., Chhatwal, Jasmeer, Marshall, Gad A., Donovan, Nancy, Jackson, Jonathan, Gatchel, Jennifer R., Hanseeuw, Bernard J., Schultz, Aaron P., Aisen, Paul S., Johnson, Keith A., Sperling, Reisa A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573651/
https://ncbi.nlm.nih.gov/pubmed/28253478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.01.018
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