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Therapeutic concentrations of digitoxin inhibit endothelial focal adhesion kinase and angiogenesis induced by different growth factors
BACKGROUND AND PURPOSE: Cardiac glycosides are Na(+)/K(+)‐ATPases inhibitors used to treat congestive heart failure and cardiac arrhythmias. Epidemiological studies indicate that patients on digitalis therapy are more protected from cancer. Evidence of a selective cytotoxicity against cancer cells h...
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| Izdano u: | Br J Pharmacol |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573418/ https://ncbi.nlm.nih.gov/pubmed/28688145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13944 |
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