Potential therapeutic targets for ALS: MIR206, MIR208b and MIR499 are modulated during disease progression in the skeletal muscle of patients

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motor neurons followed by muscle weakness, paralysis and death. The disease progression is extremely variable among patients, and reliable prognostic markers have not been identified. The aim of the study was to function...

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Publicado en:Sci Rep
Main Authors: Di Pietro, Lorena, Baranzini, Mirko, Berardinelli, Maria Grazia, Lattanzi, Wanda, Monforte, Mauro, Tasca, Giorgio, Conte, Amelia, Logroscino, Giandomenico, Michetti, Fabrizio, Ricci, Enzo, Sabatelli, Mario, Bernardini, Camilla
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573384/
https://ncbi.nlm.nih.gov/pubmed/28842714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10161-z
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