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Potential therapeutic targets for ALS: MIR206, MIR208b and MIR499 are modulated during disease progression in the skeletal muscle of patients

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motor neurons followed by muscle weakness, paralysis and death. The disease progression is extremely variable among patients, and reliable prognostic markers have not been identified. The aim of the study was to function...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Di Pietro, Lorena, Baranzini, Mirko, Berardinelli, Maria Grazia, Lattanzi, Wanda, Monforte, Mauro, Tasca, Giorgio, Conte, Amelia, Logroscino, Giandomenico, Michetti, Fabrizio, Ricci, Enzo, Sabatelli, Mario, Bernardini, Camilla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573384/
https://ncbi.nlm.nih.gov/pubmed/28842714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10161-z
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