Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae

Zika virus (ZIKV) causes significant public health concerns because of its association with congenital malformations, neurological disorders in adults, and, more recently, death. Considering the necessity to mitigate ZIKV-associated diseases, antiviral interventions are an urgent necessity. Sofosbuv...

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Publicat a:Sci Rep
Autors principals: Ferreira, André C., Zaverucha-do-Valle, Camila, Reis, Patrícia A., Barbosa-Lima, Giselle, Vieira, Yasmine Rangel, Mattos, Mayara, Silva, Priscila de Paiva, Sacramento, Carolina, de Castro Faria Neto, Hugo C., Campanati, Loraine, Tanuri, Amilcar, Brüning, Karin, Bozza, Fernando A., Bozza, Patrícia T., Souza, Thiago Moreno L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573375/
https://ncbi.nlm.nih.gov/pubmed/28842610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09797-8
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