Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae

Zika virus (ZIKV) causes significant public health concerns because of its association with congenital malformations, neurological disorders in adults, and, more recently, death. Considering the necessity to mitigate ZIKV-associated diseases, antiviral interventions are an urgent necessity. Sofosbuv...

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Publicado en:Sci Rep
Autores principales: Ferreira, André C., Zaverucha-do-Valle, Camila, Reis, Patrícia A., Barbosa-Lima, Giselle, Vieira, Yasmine Rangel, Mattos, Mayara, Silva, Priscila de Paiva, Sacramento, Carolina, de Castro Faria Neto, Hugo C., Campanati, Loraine, Tanuri, Amilcar, Brüning, Karin, Bozza, Fernando A., Bozza, Patrícia T., Souza, Thiago Moreno L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573375/
https://ncbi.nlm.nih.gov/pubmed/28842610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09797-8
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