The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

Zika virus (ZIKV) is a member of the Flaviviridae family, along with other agents of clinical significance such as dengue (DENV) and hepatitis C (HCV) viruses. Since ZIKV causes neurological disorders during fetal development and in adulthood, antiviral drugs are necessary. Sofosbuvir is clinically...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Sacramento, Carolina Q., de Melo, Gabrielle R., de Freitas, Caroline S., Rocha, Natasha, Hoelz, Lucas Villas Bôas, Miranda, Milene, Fintelman-Rodrigues, Natalia, Marttorelli, Andressa, Ferreira, André C., Barbosa-Lima, Giselle, Abrantes, Juliana L., Vieira, Yasmine Rangel, Bastos, Mônica M., de Mello Volotão, Eduardo, Nunes, Estevão Portela, Tschoeke, Diogo A., Leomil, Luciana, Loiola, Erick Correia, Trindade, Pablo, Rehen, Stevens K., Bozza, Fernando A., Bozza, Patrícia T., Boechat, Nubia, Thompson, Fabiano L., de Filippis, Ana M. B., Brüning, Karin, Souza, Thiago Moreno L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241873/
https://ncbi.nlm.nih.gov/pubmed/28098253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40920
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