CaMKII Autophosphorylation is Necessary for Optimal Integration of Ca(2+) Signals During LTP Induction but Not Maintenance

CaMKII plays a critical role in decoding calcium (Ca(2+)) signals to initiate long-lasting synaptic plasticity. However, the properties of CaMKII that mediate Ca(2+) signals in spines remain elusive. Here, we measured CaMKII activity in spines using fast-framing two-photon fluorescence lifetime imag...

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Udgivet i:Neuron
Main Authors: Chang, Jui-Yun, Parra-Bueno, Paula, Laviv, Tal, Szatmari, Erzsebet M., Lee, Seok-Jin R., Yasuda, Ryohei
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573161/
https://ncbi.nlm.nih.gov/pubmed/28521133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.04.041
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