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The Levinthal Problem in Amyloid Aggregation: Sampling of a Flat Reaction Space
The formation of amyloid fibrils has been associated with many neurodegenerative disorders, yet the mechanism of aggregation remains elusive, partly because aggregation timescales are too long to probe with atomistic simulations. A microscopic theory of fibril elongation was recently developed that...
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| Publicado en: | J Phys Chem B |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573152/ https://ncbi.nlm.nih.gov/pubmed/28129689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00253 |
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