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A novel cell-free system reveals a mechanism of circular DNA formation from tandem repeats

One characteristic of genomic plasticity is the presence of extrachromosomal circular DNA (eccDNA). High levels of eccDNA are associated with genomic instability, exposure to carcinogens and aging. We have recently reported developmentally regulated formation of eccDNA that occurs preferentially in ...

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Autori principali: Cohen, Sarit, Mechali, Marcel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC55730/
https://ncbi.nlm.nih.gov/pubmed/11410662
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