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A novel cell-free system reveals a mechanism of circular DNA formation from tandem repeats

One characteristic of genomic plasticity is the presence of extrachromosomal circular DNA (eccDNA). High levels of eccDNA are associated with genomic instability, exposure to carcinogens and aging. We have recently reported developmentally regulated formation of eccDNA that occurs preferentially in ...

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Détails bibliographiques
Auteurs principaux: Cohen, Sarit, Mechali, Marcel
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC55730/
https://ncbi.nlm.nih.gov/pubmed/11410662
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