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A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNA(Leu(UUR))
Several mitochondrial tRNA mutations have been associated with hypertension, but their pathophysiology remains poorly understood. In this report, we identified a novel homoplasmic 3253T→C mutation in the mitochondrial tRNA(Leu(UUR)) gene in a Han Chinese family with maternally inherited hypertension...
Kaydedildi:
| Yayımlandı: | J Biol Chem |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5572913/ https://ncbi.nlm.nih.gov/pubmed/28679533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787028 |
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