Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signaling in the zebrafish embryo

Circadian clock and Smad2/3/4-mediated Nodal signaling regulate multiple physiological and pathological processes. However, it remains unknown whether Clock directly cross-talks with Nodal signaling and how this would regulate embryonic development. Here we show that Clock1a coordinated mesoderm dev...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Bian, Sha-Sha, Zheng, Xu-Lei, Sun, Hua-Qin, Chen, Jian-Hui, Lu, Yi-Lu, Liu, Yun-Qiang, Tao, Da-Chang, Ma, Yong-Xin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2017
Предметы:
Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572899/
https://ncbi.nlm.nih.gov/pubmed/28687631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.794289
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