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Fragile X Mental Retardation Protein Requirements in Activity-Dependent Critical Period Neural Circuit Refinement

Activity-dependent synaptic remodeling occurs during early-use critical periods, when naïve juveniles experience sensory input. Fragile X Mental Retardation Protein (FMRP) sculpts synaptic refinement in an activity sensor mechanism based on sensory cues, with FMRP loss causing the most common herita...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Doll, Caleb A., Vita, Dominic J., Broadie, Kendal
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572839/
https://ncbi.nlm.nih.gov/pubmed/28756946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.06.046
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