Massive parallel analysis of the binding specificity of histone-like protein HU to single- and double-stranded DNA with generic oligodeoxyribonucleotide microchips

A generic hexadeoxyribonucleotide microchip has been applied to test the DNA-binding properties of HU histone-like bacterial protein, which is known to have a low sequence specificity. All 4096 hexamers flanked within 8mers by degenerate bases at both the 3′- and 5′-ends were immobilized within the...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Krylov, Alexander S., Zasedateleva, Olga A., Prokopenko, Dmitry V., Rouviere-Yaniv, Josette, Mirzabekov, Andrei D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55728/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11410675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.12.2654
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