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Drosophila histone demethylase KDM4A has enzymatic and non-enzymatic roles in controlling heterochromatin integrity

Eukaryotic genomes are broadly divided between gene-rich euchromatin and the highly repetitive heterochromatin domain, which is enriched for proteins critical for genome stability and transcriptional silencing. This study shows that Drosophila KDM4A (dKDM4A), previously characterized as a euchromati...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Colmenares, Serafin U., Swenson, Joel M., Langley, Sasha A., Kennedy, Cameron, Costes, Sylvain V., Karpen, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572651/
https://ncbi.nlm.nih.gov/pubmed/28743002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.06.014
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