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Regulation of the Sar1 GTPase Cycle Is Necessary for Large Cargo Secretion from the Endoplasmic Reticulum

Proteins synthesized within the endoplasmic reticulum (ER) are transported to the Golgi via coat protein complex II (COPII)-coated vesicles. The formation of COPII-coated vesicles is regulated by the GTPase cycle of Sar1. Activated Sar1 is recruited to ER membranes and forms a pre-budding complex wi...

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Foilsithe in:Front Cell Dev Biol
Main Authors: Saito, Kota, Maeda, Miharu, Katada, Toshiaki
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572378/
https://ncbi.nlm.nih.gov/pubmed/28879181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00075
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