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Distinct isoform-specific complexes of TANGO1 cooperatively facilitate collagen secretion from the endoplasmic reticulum

Collagens synthesized within the endoplasmic reticulum (ER) are too large to fit in conventional COPII-coated transport vesicles; thus their export from the ER requires specialized factors. TANGO1 (L) is an integral membrane protein that binds to collagen and the coatomer of vesicles and is necessar...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Maeda, Miharu, Saito, Kota, Katada, Toshiaki
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007089/
https://ncbi.nlm.nih.gov/pubmed/27413011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0196
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