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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that results from the loss of upper and lower motor neurons. One of the key pathological hallmarks in diseased neurons is the mislocalization of disease-associated proteins and the formation of cytoplasmic aggregates of these protei...
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| Publicat a: | Front Mol Neurosci |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5572252/ https://ncbi.nlm.nih.gov/pubmed/28878620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00263 |
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