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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that results from the loss of upper and lower motor neurons. One of the key pathological hallmarks in diseased neurons is the mislocalization of disease-associated proteins and the formation of cytoplasmic aggregates of these protei...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Ramesh, Nandini, Pandey, Udai Bhan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572252/
https://ncbi.nlm.nih.gov/pubmed/28878620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00263
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