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Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer
ROCK, or Rho-associated coiled coil-containing protein kinase, is a member of the AGC kinase family and has been shown to play a role in cell migration, ECM synthesis, stress-fiber assembly, and cell contraction. Increased ROCK expression has been reported in multiple pathological conditions, includ...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5571985/ https://ncbi.nlm.nih.gov/pubmed/28841710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183871 |
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