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Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look
Increased extracellular matrix (ECM) deposition is a characteristic observed in many solid tumors. Increased levels of one ECM component, namely hyaluronan (HA), leads to reduced elasticity of tumor tissue and increased interstitial fluid pressure. Multiple initial reports demonstrated that the addi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204883/ https://ncbi.nlm.nih.gov/pubmed/22053288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0136 |
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