Single nucleotide polymorphisms at miR-146a/196a2 and their primary ovarian insufficiency-related target gene regulation in granulosa cells

MicroRNAs post-transcriptionally regulate gene expression in animals and plants. The aim of this study was to identify new target genes for microRNA polymorphisms (miR-146aC>G and miR-196a2T>C) in primary ovarian insufficiency (POI). We cloned and transfected miR-146aC>G and miR-196a2T>C...

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Veröffentlicht in:PLoS One
Hauptverfasser: Cho, Sung Hwan, An, Hui Jeong, Kim, Kyung Ah, Ko, Jung Jae, Kim, Ji Hyang, Kim, Young Ran, Ahn, Eun Hee, Rah, HyungChul, Lee, Woo Sik, Kim, Nam Keun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571913/
https://ncbi.nlm.nih.gov/pubmed/28841705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183479
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