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Association of miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms with Ossification of the Posterior Longitudinal Ligament of the Cervical Spine

BACKGROUND: Ossification of the posterior longitudinal ligament (OPLL) of the spine is considered a multifactorial and polygenic disease. We aimed to investigate the association between four single nucleotide polymorphisms (SNPs) of pre-miRNAs [miR-146aC>G (rs2910164), miR-149T>C (rs2292832),...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lim, Jae Joon, Shin, Dong Ah, Jeon, Young Joo, Kumar, Hemant, Sohn, Seil, Min, Hyoung Sik, Lee, Jang Bo, Kuh, Sung Uk, Kim, Keung Nyun, Kim, Jung Oh, Kim, Ok Joon, Ropper, Alexander E., Kim, Nam Keun, Han, In Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959720/
https://ncbi.nlm.nih.gov/pubmed/27454313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159756
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