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Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies

Glioblastoma is the most common malignant brain tumor, and it carries an extremely poor prognosis. Attempts to develop targeted therapies have been hindered because the blood-brain barrier prevents many drugs from reaching tumors cells. Furthermore, systemic toxicity of drugs often limits their ther...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neurosurg
Main Authors: Jahangiri, Arman, Chin, Aaron T., Flanigan, Patrick M., Chen, Rebecca, Bankiewicz, Krystof, Aghi, Manish K.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571827/
https://ncbi.nlm.nih.gov/pubmed/27035164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2016.1.JNS151591
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