Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies

Glioblastoma is the most common malignant brain tumor, and it carries an extremely poor prognosis. Attempts to develop targeted therapies have been hindered because the blood-brain barrier prevents many drugs from reaching tumors cells. Furthermore, systemic toxicity of drugs often limits their ther...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosurg
Main Authors: Jahangiri, Arman, Chin, Aaron T., Flanigan, Patrick M., Chen, Rebecca, Bankiewicz, Krystof, Aghi, Manish K.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571827/
https://ncbi.nlm.nih.gov/pubmed/27035164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2016.1.JNS151591
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items