Acetylation of N-terminus and two internal amino acids is dispensable for degradation of a protein that aberrantly engages the endoplasmic reticulum translocon

Conserved homologues of the Hrd1 ubiquitin ligase target for degradation proteins that persistently or aberrantly engage the endoplasmic reticulum translocon, including mammalian apolipoprotein B (apoB; the major protein component of low-density lipoproteins) and the artificial yeast protein Deg1-Se...

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Detalles Bibliográficos
Publicado en:PeerJ
Main Authors: Engle, Sarah M., Crowder, Justin J., Watts, Sheldon G., Indovina, Christopher J., Coffey, Samuel Z., Rubenstein, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado: PeerJ Inc. 2017
Assuntos:
Biochemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571791/
https://ncbi.nlm.nih.gov/pubmed/28848693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3728
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