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Acetylation of N-terminus and two internal amino acids is dispensable for degradation of a protein that aberrantly engages the endoplasmic reticulum translocon

Conserved homologues of the Hrd1 ubiquitin ligase target for degradation proteins that persistently or aberrantly engage the endoplasmic reticulum translocon, including mammalian apolipoprotein B (apoB; the major protein component of low-density lipoproteins) and the artificial yeast protein Deg1-Se...

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Pubblicato in:PeerJ
Autori principali: Engle, Sarah M., Crowder, Justin J., Watts, Sheldon G., Indovina, Christopher J., Coffey, Samuel Z., Rubenstein, Eric M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571791/
https://ncbi.nlm.nih.gov/pubmed/28848693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3728
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