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Crosstalk between Smad2/3 and specific isoforms of ERK in TGF‐β1‐induced TIMP‐3 expression in rat chondrocytes

This study investigated the roles of ERK1 and ERK2 in transforming growth factor‐β1 (TGF‐β1)‐induced tissue inhibitor of metalloproteinases‐3 (TIMP‐3) expression in rat chondrocytes, and the specific roles of ERK1 and ERK2 in crosstalk with Smad2/3 were investigated to demonstrate the molecular mech...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhu, Yanhui, Gu, Jianhua, Zhu, Tong, Jin, Chen, Hu, Xiaopeng, Wang, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571561/
https://ncbi.nlm.nih.gov/pubmed/28230313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13099
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