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A design for phase I trials in completely or partially ordered groups

We propose a design for dose finding for cytotoxic agents in completely or partially ordered groups of patients. By completely ordered groups, we mean that prior to the study, there is clinical information that would indicate that for a given dose, the groups can be ordered with respect to the proba...

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Detalhes bibliográficos
Publicado no:Stat Med
Autor principal: Conaway, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571448/
https://ncbi.nlm.nih.gov/pubmed/28384843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7295
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