Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi

INTRODUCTION: Pneumococcal infections cause a high death toll in Sub Saharan Africa (SSA) but the recently rolled out pneumococcal conjugate vaccines (PCV) will reduce the disease burden. To better understand the population impact of these vaccines, comprehensive analysis of large collections of pne...

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Udgivet i:Vaccine
Main Authors: Chaguza, Chrispin, Cornick, Jennifer E., Andam, Cheryl P., Gladstone, Rebecca A., Alaerts, Maaike, Musicha, Patrick, Peno, Chikondi, Bar-Zeev, Naor, Kamng'ona, Arox W., Kiran, Anmol M., Msefula, Chisomo L., McGee, Lesley, Breiman, Robert F., Kadioglu, Aras, French, Neil, Heyderman, Robert S., Hanage, William P., Bentley, Stephen D., Everett, Dean B.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571440/
https://ncbi.nlm.nih.gov/pubmed/28711389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.07.009
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