Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst Streptococcus pneumoniae in Malawi

OBJECTIVES: This study aimed to define the molecular basis of co-trimoxazole resistance in Malawian pneumococci under the dual selective pressure of widespread co-trimoxazole and sulfadoxine/pyrimethamine use. METHODS: We measured the trimethoprim and sulfamethoxazole MICs and analysed folA and folP...

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Detalhes bibliográficos
Main Authors: Cornick, Jennifer E., Harris, Simon R., Parry, Christopher M., Moore, Michael J., Jassi, Chikondi, Kamng'ona, Arox, Kulohoma, Benard, Heyderman, Robert S., Bentley, Stephen D., Everett, Dean B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886935/
https://ncbi.nlm.nih.gov/pubmed/24080503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt384
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