MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption

Rilpivirine (TMC278) is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI) representing an effective component of combination antiretroviral therapy (cART) in the treatment of HIV-positive patients. Many antiretroviral drugs commonly used in cART are substrates of ATP-binding cass...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Reznicek, Josef, Ceckova, Martina, Ptackova, Zuzana, Martinec, Ondrej, Tupova, Lenka, Cerveny, Lukas, Staud, Frantisek
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571350/
https://ncbi.nlm.nih.gov/pubmed/28696229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00837-17
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